Connect with us

Health

Frequent Immune Cells Can Significantly Slow Tumor Growth – Healing Practice

Published

on

Shown for the first time: immune cells inhibit tumor growth

Neutrophil granulocytes, in brief neutrophils, represent the largest proportion of white blood cells, their main task is to defend against pathogens such as bacteria or viruses. Researchers have now found that these immune cells even while fighting Cancer be able to help.

A research team has been able to show for the first time that a common immune cell can significantly slow the growth of tumors in the early stages. The body’s defense cells, known as neutrophil granulocytes, can improve cancer patients’ chances of survival under certain conditions. The results of the study were published in the journal “Cell reports“published.

tumor promoting properties

As in a stream Message At the University of Duisburg-Essen, neutrophil granulocytes, or neutrophils for short, had a pretty bad reputation up until now.

If they circulate to a greater extent in cancer patients in the form of so-called tumor-associated neutrophils, this can lead to further spread of cancer, for example in the case of head and neck cancer. Unfortunately, there are only a few options so far tumor promoting properties to block these cells.

New findings from private lecturer Dr. However, Jadwiga Jablonska and her team at the ENT Clinic at Essen University Hospital (UK Essen) show that neutrophil granulocytes aren’t always the bad guys. defense against cancer can support.

Neutrophils change shape

“Neutrophil granulocytes are able to absorb tumor antigens, migrate to lymph nodes in early stages of cancer, and activate immune cells”explains Dr. Ekaterina Pylaeva, first author of the study.

“Previously, neutrophils were thought to inhibit the anti-cancer immune response; now we know that they can also be powerful stimulants., adds the head of the Jablonska study. Therefore, an accumulation of these cells in the early stage cancer a positive prognosis for patients.

In later stages of cancer, however, an accumulation of these immune cells promotes tumor growth, the researchers observed. Then the neutrophils change shape from a anti-tumor phenotype to a tumor promoter.

With this knowledge, attempts can now be made to address the mechanism therapeutically and so chances of survival of the people concerned to increase. (ad)

Author and source information

This text corresponds to the specifications of the specialized medical literature, medical guidelines and current studies and has been verified by health professionals.

Sources:

  • University of Duisburg-Essen: Proved for the first time: immune cells inhibit tumor growth, (Accessed: August 17, 2022), University of Duisburg-Essen
  • Ekaterina Pylaeva, Georg Korschunow, Ilona Spyra, Sharareh Bordbari, Elena Siakaeva, Irem Ozel, Maksim Domnich, Anthony Squire, Anja Hasenberg, Kruthika Thangavelu, Timon Hussain, Moritz Goetz, Karl S. Lang, Matthias Gunzer, Wiebke Hansen, Jan Buer, Agnes Bankfalvi, Stephan Lang, Jadwiga Jablonska: During the early stages of cancer, neutrophils initiate anti-tumor immune responses in tumor-draining lymph nodes; in: Cell Reports, (published: 08/16/2022), Cell reports

Important note:
This article contains general advice only and should not be used for self-diagnosis or treatment. It cannot substitute a visit to the doctor.

Continue Reading
Click to comment

Leave a Reply

Your email address will not be published.

Trending