Microorganisms open new perspectives – healing practice

Interactions between bacteria and cancer cells

microorganismsthat inhabit the human body can be ours Health affect to a large extent. The best example is intestinal bacteriatheir influence on our metabolism increasingly documented. According to a recent study, microbes also seem to play an important role in the development of certain cancer to play

researchers of Rutgers Cancer Institute of New Jersey identified certain microorganisms that multiply in people with pancreatic tumors inflammation and worst survival rates is connected. The results were recently published in the journal “cancer cell“published.

What role do bacteria play in cancer?

Not only in our intestines, but also in other organs such as the lungs and the pancreas different micro-organisms settle, which can influence the functioning of the organs.

As part of the current study, the Rutgers Cancer Institute working group checked whether the microbes cancer progression radiation. To do this, the team analyzed whether bacteria are present in pancreatic tumors and whether they have an impact on cancer progression or treatment.

Pancreatic cancer is one of the most dangerous types of cancer

pancreatic cancer is relatively rare, but particularly aggressive. The chances of survival for those affected are among the lowest of all types of cancer. Due to the absence of symptoms in the early stages of the disease pancreatic tumors often discovered only after they have already begun to disperse.

Bacteria involved in the progression of pancreatic cancer

Researchers have succeeded in identifying specific microbes that are associated with a bad prognosis associated with pancreatic tumors.

Microorganisms represent a new and promising point of attack which could influence the course of the disease. In addition, bacteria could Early detection of pancreatic cancer to be used.

RNA sequences assessed

The team has developed a new genomic approach that RNA sequences have been assessed. In this way, it was possible to distinguish which sequences Human and that microbial origin are.

“This new technique allowed us to identify tumor-associated microbes while simultaneously measuring host cell activity”Explain professor doctor Subhajyoti Déwith who Dr Martin Blaser The lead author of the study is

Symbiosis between cancer cells and certain bacteria

With the new approach, the working group was able to determine that certain bacteria were associated with certain types of cells in the tumor that are not normally found in pancreatic tissue. Most of the bacteria found were in tumor cells.

The number of bacteria of this type present correlates with the cancer cell activity. According to the research team, the signatures of the microbes found allow conclusions to be drawn about the expected course of pancreatic cancer.

New approaches for the diagnosis and treatment of cancer

Additionally, the researchers found that immune cells mainly react only to bacteria, but not to bacteria-associated cancer cells.

“Our findings shed new light on why pancreatic cancer is so difficult to treat”stress doctor fan. According to him, a better understanding of the Interactions between bacteria and cancer cells show new therapeutic approaches against cancer. (vb)